Thursday, February 3, 2011

Thermogelation Additives

The thermogelation properties of low molecular weight triblock copolymers (like PolyVivo AK12 and AK19) can be fine-tuned using either PEG1000 to slightly lower the gelation temperature or NaSCN to raise the gelation temperature. PolyVivo polymers can be purchased at

The tuning process is described more thoroughly in the following research paper:

Myung Seob Shim, Hyung Tak Lee, Woo Sun Shim, Insun Park, Hyunjung Lee, Taihyun Chang,Sung Wan Kim, Doo Sung Lee “Poly(D,L-lactic acid-co-glycolic acid)-b-poly(ethylene glycol)-b-poly (D,L-lactic acid-co-glycolic acid) triblock copolymer and thermoreversible phase transition in water” J Biomed Mater Res 61: 188–196, 2002

Link To Full-text
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