Thursday, June 27, 2013

Gullotti et. al. AK30 nanoparticles



Gullotti et. al. mixed PLGA with a PolyVivo AK30 (mPEG-PLGA 5000-4000, www.polyscitech.com) at a 75:25 ratio and processed via sonication-emulsion into nanoparticles for drug delivery.  When loaded with fluorescent PLGA-FITC the particles had an average size of 179.8nm with a zeta potential of -11.2. When loaded with paclitaxel the particles had an average size of 248.8nm and a zeta potential of -7.5 with an average PTX load of 20.6% (w/w%). Find out more about their research here (http://link.springer.com/article/10.1007/s11095-013-1039-y)
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