PolySciTech (www.polyscitech.com) has just launched a
new product mPEG-PEI (Polyvivo AK86) for use as a delivery vehicle for nucleic
acids including DNA, siRNA, mRNA, and miRNA.
Recently this type of polymer was utilized to deliver siRNA to prostate
cancer cells as a therapeutic method to knockdown EZH2 gene expression which is
responsible for prostate cancer progression. Read more: Wu, Yinxia, Junjie Yu,
Yongbiao Liu, Lin Yuan, Hang Yan, Jing Jing, and Guoping Xu. "Delivery of
EZH2-shRNA with mPEG-PEI nanoparticles for the treatment of prostate cancer in
vitro." International journal of molecular medicine 33, no. 6 (2014):
1563-1569. http://www.ingentaconnect.com/content/sp/ijmm/2014/00000033/00000006/art00023
Blog dedicated to answering technical questions in an open format relating to PolySciTech (A division of Akina, Inc.) products.
Wednesday, June 18, 2014
New PolySciTech Product mPEG-PEI copolymer for DNA/RNA delivery as cancer therapy
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