A new product line is available from PolySciTech:Akina and
this one is 3DCellMaker (www.3DCellMaker.com).
3DCellMaker is a thermogelling synthetic substrate which allows for the
easy growth of cells in a 3D pattern without requiring the use of complex
hanging drop, magnetism, or other techniques. The unique polymer formulation
allows for 3DCellMaker to be mixed at low temperature (5-10C) with media
generating a self-gelling system capable of aiding the growth of tumors and
other cells into 3D shapes such as spheroids. There are two versions available.
One is optimized for seeding the cells on top of the solidified gel while the
other is optimized for seeding the cells in the cold-liquid gel and then
warming to transition. In both cases the gel sets and allows the cells to grow
in a 3D pattern over the course of 2-12 days after which time the gel is washed
away. This system allows for easy generation of a more accurate representation
of cancer cell modeling than tradition 2D flat plate and at a lower price than
xenograft models. No specialized equipment is required for 3DCellMaker as it
can generate spheroids in any conventional well-plate or other typical
incubation plasticware in a typical 5% CO2/37C incubator regardless of
container properties or geometric orientation.
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