Friday, June 19, 2015

AK100, A thermogel with improved gelation at 37C

PolySciTech ( provides a wide array of thermogelling polymers. One of these, AK100 P(DL)La-PEG-P(DL)La 1700-1500-1700 forms a very strong thermogel when dissolved as a 20% w/v solution in water as shown in the video.  For this video 1g of AK100 was dissolved at 5-10C in 5ml of water with shaking for 1-2 days and subsequently the solution was warmed to room temperature. At this temperature the polymer solution is very fluid like water. Afterwards it was placed in a 37 C incubator and equilibriated for 30 min to fully warm the solution. As can be seen, turning the vial upside down shows that a strong and stable gel is formed by this polymer.

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