PolySciTech
division of Akina, Inc (www.polyscitech.com)
provides a wide array of research products including USA distribution of Flamma
Fluor dyes produced from BioActs. Recently two review articles came out which
discuss the use of drug nanocrystals for chemotherapeutic applications. These
articles discuss hybrid nanocrystal applications in which Flamma Fluor dyes are
incorporated into the drug nanocrystals in order to render them fluorescent in
the near-IR region. The applications of such nanocrystals and the near-IR
imaging towards theranostics is discussed. Read more: Lu, Yi, Yan Chen, Richard
A. Gemeinhart, Wei Wu, and Tonglei Li. "Developing nanocrystals for cancer
treatment." Nanomedicine 10, no. 16 (2015): 2537-2552. Full-Text: http://www.researchgate.net/profile/Yi_Lu23/publication/281169353_Developing_nanocrystals_for_cancer_treatment/links/55dd25fb08ae591b309ac4dc.pdf
“Abstract: Nanocrystals are carrier-free solid
drug particles that are sized in the nanometer range and have crystalline
characteristics. Due to high drug loading (as high as 100%) – free of organic
solvents or solubilizing chemicals – nanocrystals have become attractive in the
field of drug delivery for cancer treatment. Top–down and bottom–up approaches
have been developed for preparing anticancer nanocrystals. In this review,
preparation methods and in vivo performance of anticancer nanocrystals are
discussed first, followed by an introduction of hybrid nanocrystals in cancer
theranostics.”
Also you can read
about this application of these dyes in another review article here: Kaur, Veerpal,
Tejinder Singh, Supandeep Singh Hallan Nidhi, and Neeraj Mishra. "Surface
Modified Nanoparticulate Carriers for the Targeted Treatment of Breast
Cancer." http://www.researchgate.net/profile/Neeraj_Mishra13/publication/272822193_Surface_Modified_Nanoparticulate_Carriers_for_the_Targeted_Treatment_of_Breast_Cancer/links/54f6f3710cf2ccffe9d82339.pdf
“Abstract: Breast
cancer left overs one of the greatest common metastasis disease in females.
Advanced diagnostic devices and better understanding of tumour biology can extend
the better therapeutic outcomes. Nanotechnology is a tool that helps in cancer
diagnosis and treatment therapy. Many nanocarriers such as solid lipid
nanoparticles, magnetic nanoparticles, nanocrystals, nanogels, nano-lipid nanocarriers,
biodegradable nanoparticles, liposomes, and dendrimers are introduced to
improve the therapeutic efficacy of antineoplastic agents. Surface modified
target drug delivery system has the potential to increase the therapeutic
effects and also reduce the cytotoxicity of breast cancer. Different approaches
have been explored for treatment of breast cancer. This review describes the recent
advances in the development of nanocarriers used for the targeted treatment of
breast cancer. It also focuses on etiology, risk factor and conventional
therapy of breast cancer. KEYWORDS: Breast Cancer; Nano-carriers; Tumor
Targeting; Ligands; Receptor.”
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