Thursday, March 3, 2016

New publication using PST hydrogel template and PolySciTech categories listing

PolySciTech Division of Akina, Inc. (www.polyscitech.com) provides a wide array of biodegradable polymer research products. Over the years, our catalog has expanded to include upwards of 500 products. In order to aid in finding the product you are looking for in our catalog we have created a category breakdown of the catalog for quick searching. You can see this one here: https://akinainc.com/polyscitech/products/polyvivo/categories.php.



Additionally, a recent research publication utilizes Akina’s hydrogel template technology in order to generate a series of shaped microparticles to determine shape effects on cellular interactions. Read more here: He, Yuanzu, and Kinam Park. "Effects of the Microparticle Shape on Cellular Uptake". Molecular Pharmaceutics (2016) (http://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.5b00992)

“Abstract: Physical forms of microparticles and nanoparticles, such as the size, charge, and shape, are known to affect endocytosis. Improving the physical designs of the drug carriers can increase the drug uptake efficiency and the subsequent drug efficacy. Simple shapes, such as sphere and cylinder, have been studied for their ability for endocytosis. To have a better understanding of the shape effect on cellular uptake, different particle shapes were prepared, using the keyboard character shapes, and their impacts on cellular uptake were examined. The results showed that shapes with higher aspect ratios and sharper angular features have a higher chance of adhering to the cells and become internalized by the cancer cells. The local interaction between the cell membrane and the part of the microparticle in contact with the cell membrane also plays a crucial role in determining the outcome. Keywords: microparticle shape; size; aspect ratio; endocytosis; cellular uptake”
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