New publication using PST hydrogel template and PolySciTech categories listing
PolySciTech Division of
Akina, Inc. (www.polyscitech.com) provides a wide array of biodegradable
polymer research products. Over the years, our catalog has expanded to include
upwards of 500 products. In order to aid in finding the product you are looking
for in our catalog we have created a category breakdown of the catalog for
quick searching. You can see this one here: https://akinainc.com/polyscitech/products/polyvivo/categories.php.
Additionally, a recent
research publication utilizes Akina’s hydrogel template technology in order to
generate a series of shaped microparticles to determine shape effects on
cellular interactions. Read more here: He, Yuanzu, and Kinam Park.
"Effects of the Microparticle Shape on Cellular Uptake". Molecular
Pharmaceutics (2016) (http://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.5b00992)
“Abstract: Physical
forms of microparticles and nanoparticles, such as the size, charge, and shape,
are known to affect endocytosis. Improving the physical designs of the drug
carriers can increase the drug uptake efficiency and the subsequent drug
efficacy. Simple shapes, such as sphere and cylinder, have been studied for
their ability for endocytosis. To have a better understanding of the shape
effect on cellular uptake, different particle shapes were prepared, using the
keyboard character shapes, and their impacts on cellular uptake were examined.
The results showed that shapes with higher aspect ratios and sharper angular
features have a higher chance of adhering to the cells and become internalized
by the cancer cells. The local interaction between the cell membrane and the
part of the microparticle in contact with the cell membrane also plays a
crucial role in determining the outcome. Keywords: microparticle shape; size;
aspect ratio; endocytosis; cellular uptake”
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