PLGA in FDA approved products

Since PLGA is sold at PolySciTech (www.polyscitech) I often receive questions about what products have PLGA in them that have been approved by FDA. Below is a quick list of these. As can be seen, there is a long and successful history of using PLGA as a safe and effective drug carrier system.

Product Name	Drug	Type	Duration	Dose	Approved
Zoladex	Goserelin	Solid implant	1,3 months	3.6 mg/month	1989
Lurpon	Leuprolide	Microparticle	1-4 months	7.5 mg/month	1989
Sandostatin	Octreotide	Microparticle	1 month	20 mg/month	1998
Atridox	Doxycycline	In situ gel	1 week	42.5 mg/week	1998
Nutropin	Somatotropin	Microparticle	1 month	13.5 mg/month	1999
Trelstar	Triptorelin	Microparticle	1-6 months	3.75 mg/month	2000, 2010
Superfact	Buserelin	Solid implant	2,3 months	3.15 mg/month	2000
Somatuline	Lanreotide	Microparticle	1 month	60 mg/month	2000
Arestin	Minocycline	Microparticle	2 weeks	0.5 mg/week	2001
Eligard	Leuprolide	In situ gel	1-6 months	7.5 mg/month	2002
RisperidalConsta	Risperidone	Microparticle	2 weeks	12.5 mg/week	2003
Vivitrol	Naltrexone	Microparticle	1 month	380 mg/month	2006
Ozurdex	Dexamethasone	Solid implant	3 months	0.23 mg/month	2009
Propel	Mometasone	Solid implant	1 month	370 mg/month	2011
Bydureon	Exenatide	Microparticles	1 week	2 mg/week	2012
Lupaneta Pack	Leuprolide	Microparticles	3 months	3.75 mg/month	2012