Friday, May 27, 2016

PLGA in FDA approved products

Since PLGA is sold at PolySciTech (www.polyscitech) I often receive questions about what products have PLGA in them that have been approved by FDA. Below is a quick list of these. As can be seen, there is a long and successful history of using PLGA as a safe and effective drug carrier system.

Product Name
Drug
Type
Duration
Dose
Approved
Zoladex
Goserelin
Solid implant
1,3 months
3.6 mg/month
1989
Lurpon
Leuprolide
Microparticle
1-4 months
7.5 mg/month
1989
Sandostatin
Octreotide
Microparticle
1 month
20 mg/month
1998
Atridox
Doxycycline
In situ gel
1 week
42.5 mg/week
1998
Nutropin
Somatotropin
Microparticle
1 month
13.5 mg/month
1999
Trelstar
Triptorelin
Microparticle
1-6 months
3.75 mg/month
2000, 2010
Superfact
Buserelin
Solid implant
2,3 months
3.15 mg/month
2000
Somatuline
Lanreotide
Microparticle
1 month
60 mg/month
2000
Arestin
Minocycline
Microparticle
2 weeks
0.5 mg/week
2001
Eligard
Leuprolide
In situ gel
1-6 months
7.5 mg/month
2002
RisperidalConsta
Risperidone
Microparticle
2 weeks
12.5 mg/week
2003
Vivitrol
Naltrexone
Microparticle
1 month
380 mg/month
2006
Ozurdex
Dexamethasone
Solid implant
3 months
0.23 mg/month
2009
Propel
Mometasone
Solid implant
1 month
370 mg/month
2011
Bydureon
Exenatide
Microparticles
1 week
2 mg/week
2012
Lupaneta Pack
Leuprolide
Microparticles
3 months
3.75 mg/month
2012
Post a Comment