Tuesday, February 6, 2024

PGACL from PolySciTech used in development of flexible electronics for implantable devices

 


Transient electronics describe electronic systems which have the ability to dissolve after the intended use. Researchers at Korea University, SK Hynix, Hanwha Systems Co., Ltd., North Carolina State University, Samsung Electronics Co., Ltd, Poly(glycolide-co-caprolactone) (APB004, APB007, APB008) from PolySciTech Division of Akina, Inc. (www.polyscitech.com) to create a stretchy platform for creating degradable backing for implantable electronics. This technology holds promise to provide for a biological-electrical interface. Read more: Shin, Jeong-Woong, Dong-Je Kim, Tae-Min Jang, Won Bae Han, Joong Hoon Lee, Gwan-Jin Ko, Seung Min Yang et al. "Highly Elastic, Bioresorbable Polymeric Materials for Stretchable, Transient Electronic Systems." Nano-Micro Letters 16, no. 1 (2024): 1-13. https://link.springer.com/article/10.1007/s40820-023-01268-2

“Highlights: The paper introduces a bioresorbable elastomer, poly(glycolide-co-ε-caprolactone) (PGCL), with remarkable mechanical properties, including high elongation-at-break (< 1300%), resilience, and toughness (75 MJ m−3) for soft and transient electronics. Fabrication of conducting polymers with PGCL yields stretchable, conductive composites for transient electronic devices, functioning reliably under external strains. The study demonstrates the feasibility of a disintegrable electronic suture system with on-demand drug delivery for rapid recovery of post-surgical wounds on soft, time-dynamic tissues or versatile biomedical areas of interest. Substrates or encapsulants in soft and stretchable formats are key components for transient, bioresorbable electronic systems; however, elastomeric polymers with desired mechanical and biochemical properties are very limited compared to non-transient counterparts. Here, we introduce a bioresorbable elastomer, poly(glycolide-co-ε-caprolactone) (PGCL), that contains excellent material properties including high elongation-at-break (< 1300%), resilience and toughness, and tunable dissolution behaviors. Exploitation of PGCLs as polymer matrices, in combination with conducing polymers, yields stretchable, conductive composites for degradable interconnects, sensors, and actuators, which can reliably function under external strains. Integration of device components with wireless modules demonstrates elastic, transient electronic suture system with on-demand drug delivery for rapid recovery of post-surgical wounds in soft, time-dynamic tissues. Biodegradable elastomer; Conductive polymer composites; Biomedical device; Transient electronics”

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BPR (Biotech Pharma Research) Conference (April 10, 2024, KPTC West Lafayette, IN) is a​ free ​scientific/​networking conference hosted by Akina (http://bprconference.com/​).

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