Folate-PEG, PEG-PLLA polymers from PolySciTech used in development of targeted nanoparticle photodynamic therapy of cancer

Cancer therapy suffers from drawbacks due to the non-specific nature of chemotherapy as well as the invasive nature of surgical and radiological means of treatment. Targeted therapies which primarily affect the cancerous tissue without damaging healthy tissue hold promise to reduce the side-effects of cancer treatment. Recently, researchers at Wroclaw University (Poland) used mPEG-PLLA (AK004) and Folate-PEG-COOH (AE003) from PolySciTech (www.polyscitech.com) to create targeted nanoparticles for phototherapy. This research holds promise to improve treatment regiments for cancers. Read more: Lamch, Łukasz, Julita Kulbacka, Magda Dubińska-Magiera, Jolanta Saczko, and Kazimiera A. Wilk. "Folate-directed zinc (II) phthalocyanine loaded polymeric micelles engineered to generate reactive oxygen species for efficacious photodynamic therapy of cancers." Photodiagnosis and Photodynamic Therapy (2019). https://www.sciencedirect.com/science/article/pii/S1572100019300304

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