Tuesday, December 22, 2020

Patents published using PEG-PLA block polymers and PLGA from PolySciTech for drug delivery applications

 

Much of the research work around PolySciTech products comes out as scientific research articles. However, in addition to these a great deal of research comes out in the form of patents on various developments created using PolySciTech products for an array of biomedical applications. Recently, two patents have been published using PolySciTech products. A recent patent by Phosphorex uses mPEG-PLA (AK031) from PolySciTech (www.polyscitech.com) to create encapsulated particles for drug delivery applications. Wu, Bin, and Paul Boucher. "NOVEL PHARMACEUTICAL FORMULATIONS CONTAINING INDIRUBIN AND DERIVATIVES THEREOF AND METHODS OF MAKING AND USING THE SAME." U.S. Patent Application 16/986,526, filed December 10, 2020. https://www.freepatentsonline.com/y2020/0383931.html “The invention described herein provides various indirubin compositions for treating diseases.” A recent patent by Northwestern University uses PLGA from PolySciTech (www.polyscitech.com) as part of nanoparticle formulation. Read more: Scott, Evan A., Guillermo A. Ameer, Jacqueline A. Burke, Sean D. Allen, and Sijia Yi. "POLY (ETHYLENE GLYCOL)-BLOCK-POLY (PROPYLENE SULFIDE) NANOCARRIER PLATFORM FOR ENHANCED EFFICACY OF IMMUNOSUPPRESSIVE AGENTS." U.S. Patent Application 16/891,391, filed December 10, 2020. https://www.freepatentsonline.com/y2020/0383917.html. “Provided herein are nanocarriers for delivery of immunosuppressive agents. In some embodiments, provided herein are nanocarriers comprising a core comprising a poly(ethylene glycol)-block-poly(propylene sulfide) copolymer and least one therapeutic agent. In some embodiments, the nanocarriers may further comprise a targeting ligand displayed on a surface of the nanocarrier. The at least one therapeutic agent may be an anti-inflammatory agent. The disclosed nanocarriers may be incorporated into pharmaceutical compositions for use in methods of treating an inflammatory condition or preventing transplantation rejection in a subject.”

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