Wednesday, August 21, 2013

3D printing with Polycaprolactone

Recent research has optimized the parameters for 3D printing with polycaprolactone. In this research synthesized PCL with a molecular weight near 79 kDa (similar to PolyVivo  productAP11) was printed successfully using a Bioscaffolder (Envisiontec GmbH, Gladbeck, Germany) by extruding the molten polymer through a 23Ga heated nozzle at 110C and strands were applied onto a collector plate in a layer-by-layer method at a speed of 350mm/min.  The strand pattern was rotated at 90° angles in between layers which created square pores. The distance between strands was 0.9 mm with a spindle speed of 200 rpm.  The resultant elastic modulus of PCL is ~59MPa but the modulus (compressive) of the scaffold was around 10MPa. Note the density of crystalline and the amorphous PCL is 1.200 and 1.021 g/cm3, respectively.

Seyednejad, Hajar, Debby Gawlitta, Wouter JA Dhert, Cornelus F. van Nostrum, Tina Vermonden, and Wim E. Hennink. "Preparation and Characterization of a 3D-printed Scaffold Based on a Functionalized Polyester for Bone Tissue Engineering Application." Functionalized Polyesters 7, no. 5 (2012): 87.

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