Thursday, August 21, 2014

Review Article discusses polymers for drug delivery

PolySciTech (www.polyscitech.com) provides a wide array of biodegradable polymers and block copolymers for drug delivery applications. A recent review article details several of these applications regarding drug delivery. Read more: Behera, Basanta Kumar, Ranjit Mohapatra, and Sunit Kumar Sahoo. "Novel Functionalized Polymers in Drug Delivery: A Brief Review." Journal of Current Pharma Research 4, no. 3 (2014): 1201-1210. This article is available in full-text here http://www.jcpronline.in/images/articles/1201-1210.pdf

 “Abstract: During the last few years, the science and technology of functionalized biodegradable polymers have received considerable interest in the field of polymer chemistry as well as pharmaceuticals. The novel concept behind the approaches is to produce improved polymers with enhanced desirable properties. In the recent years the functionalized polymers are synthesized and used in the form of Polymeric micelle, Polymer vesicles / Polymersomes, Films, Nanocomposite particles, “Smart” polymer conjugates, Hydrogels, Nanogels / Hydrogel nanoparticles, Mesoporous silica nanoparticles, Magnetic nanoparticles (MNPs) and Nanoparticles for improving pharmaceutical properties and therapeutic efficacy of the drugs. The functionalized polymers not only used as carriers but also improves the complications associated with the novel drug delivery formulations like: reduce P-glycoprotein drug efflux function and prevent drug resistance, improves drug loading, improved gene delivery in mesenchymal stem cells etc. In future these functionalized polymers are going to play a vital role in pharmaceutical and biological sciences in order to improve the therapeutic efficacy of a desired drug in field of cancer therapy, tuberculosis therapy, antimicrobial therapy and gene delivery. Keywords: Biodegradable, films, nanoparticles, nanogels, smart polymer conjugates.”
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