PolySciTech (www.polyscitech.com)
provides a wide variety of block copolymers as well as reactive
intermediates. A variety of new
intermediates are now available from PolySciTech based on the PLGA-PEG diblock
configuration and possessing a variety of reactive endcaps including
iodoacetamide (PolyVivo AI83), bromoacetamide (PolyVivo AI84), and azide
(PolyVivo AI85). Read more about the conjugation chemistry which can be used to
couple these to ligands here: Roberts, M. J., M. D. Bentley, and J. M. Harris.
"Chemistry for peptide and protein PEGylation." Advanced drug
delivery reviews 54, no. 4 (2002): 459-476. Full-Text: http://www.creativepegworks.com/chemistry_for_peptide_and_protein_pegylation.pdf
Blog dedicated to answering technical questions in an open format relating to PolySciTech (A division of Akina, Inc.) products.
Friday, September 5, 2014
New PLGA-PEG-azide/bromoacetamide/iodoacetamide products from PolySciTech for custom ligand conjugation
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