Tuesday, August 25, 2015

New Fluorescent dye conjugated block copolymers available from PolySciTech

PolySciTech (www.polyscitech.com) provides a wide array of biodegradable block copolymers including fluorescently conjugated block copolymers. These types of polymers are particularly useful for researchers who are performing studies where visualizing and tracking the polymer is of value. Most notably, this is particularly useful for nanoparticles since they are small and difficult to see under a microscope. With a fluorescent dye conjugated onto the polymer, tracking nanoparticle formulations made of these materials is an easy way to confirm valuable parameters relevant to targeted delivery such as accumulation and cellular uptake. These new polymers are available online as PolyVivo AV19, AV20, and AV21 (https://akinainc.com/polyscitech/products/polyvivo/sequential.php#PolymerVisualization). Similar, lab-made, polymers have been used previously to track nanoparticles and you can read about this usage here: Wang, Hai, Ying Zhao, Yan Wu, Yu-lin Hu, Kaihui Nan, Guangjun Nie, and Hao Chen. "Enhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticles." Biomaterials 32, no. 32 (2011): 8281-8290. http://www.sciencedirect.com/science/article/pii/S0142961211008039

Post a Comment