PolySciTech (www.polyscitech.com) has been named “Made
in Indiana” manufacturer of the week (http://www.mep.purdue.edu/made/products.aspx?company=249).
Additionally PST provides a wide array of PLGA-PEG copolymers. These types of
copolymers have been the focus of a recent review article with respect to their
drug delivery properties. Read more: http://dx.doi.org/10.1016/j.jconrel.2014.03.026
“Abstract: In the paper, we begin
by describing polyethylene glycol–poly lactic acid-co-glycolic acid (PEG–PLGA)
which was chosen as a typical model copolymer for the construction of
nano-sized drug delivery systems and also the types of PEG–PLGA copolymers that
were eluted. Following this we examine the structure-influenced drug delivery
applications including nanoparticles, micelles and hydrogels. After that, the
preparation methods for nano-sized delivery systems are presented. In addition,
the drug loading mode of PEG–PLGA micelles is divided into three aspects.
Finally, the drug release profiles of PEG–PLGA micelles, both in terms of their
in vitro and in vivo characteristics, are represented. PEG–PLGA copolymers are
very suitable for the construction of micelles as carriers for insoluble drugs.
This article reviews the structure and the different structure-influenced
applications of PEG–PLGA copolymers, concentrating on the application of PEG–PLGA
micelles. Keywords PEG–PLGA copolymers; Structure types; Drug
delivery applications; Drug loading; Drug release; Target delivery”
No comments:
Post a Comment