Blog dedicated to answering technical questions in an open format relating to PolySciTech (A division of Akina, Inc.) products.
Wednesday, February 22, 2017
New whitepaper on thermogelling PLCL-PEG-PLCL aqueous storage stability as a ready-to-go solution
PolySciTech
division of Akina, Inc (www.polyscitech.com)
provides a wide array of biodegradable polymers. One class of these is
thermogelling polymers which can dissolve in cold water and then form into a
solid gel once the water is warmed above the LCST. In some situations, one may
want to dissolve the polymer in an aqeous solution and then store it in this ready-to-go
condition for some time prior to use. As these polymers are hydrolysable, there
is a finite span of time that this gel solution can be stored. Recently,
accelerated degradation testing was performed using PLCL-PEG-PLCL PolyVivo
AK109. The PLCL blocks provide for slower degradation as compared with PLGA
blocks and this study was designed to see how long these thermogels can be
store. You can see more on this here (http://akinainc.com/pdf/AK109%20storage%20stability.pdf)
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