Cancer survival rates and prognosis depends on both location
and type of cancer. For breast-cancer, one of the most devastating and
difficult to treat forms is what is referred to as triple-negative breast
cancer. This breast cancer lacks typical markers and factors, such as HER,
which normal breast cancers possess. Since these markers are usually targeted
in traditional therapy, this makes treating this type of cancer very difficult.
Additionally, these types of cancer tend to grow aggressively. Recently,
researchers from University of Massachusetts Lowell used Polyvivo mPEG-PLGA (AK037)
and PLGA-PEG-Mal (AI020) from PolySciTech (www.polyscitech.com)
to develop unique phototriggered nanoparticles to treat breast cancer which
respond to near-infrared light to destroy the tumors. This holds promise for
improved treatment options for this often lethal and difficult to treat disease.
Read more: Jadia, Rahul, Janel Kydd, and Prakash Rai. "Remotely
Phototriggered, Transferrin‐Targeted Polymeric Nanoparticles for the Treatment
of Breast Cancer." Photochemistry and Photobiology. http://onlinelibrary.wiley.com/doi/10.1111/php.12903/full
Blog dedicated to answering technical questions in an open format relating to PolySciTech (A division of Akina, Inc.) products.
Thursday, February 15, 2018
Mal-PEG-PLGA and mPEG-PLGA from PolySciTech used to develop phototherapy nanoparticles for triple-negative breast cancer treatment
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