Fluorescent PLGA from PolySciTech used in development of wearable biomedical sensing system

For chronic illness and other applications the convenience and ease of a wearable device (such as a transdermal patch or a wrist-watch type device) provides for several advantages over continuous monitoring and manual medicinal administrations. Recently, researchers at Griffith University, Berghofer Medical Research Institute, and University of South Australia, used fluorescent PLGA-AF488 (custom-made) from PolySciTech (www.polyscitech.com) as part of a wearable smart-device to control drug delivery in response to changes in mechanical forces such as changes in pulse or other factors. This research holds promise for the development of devices for use in a wide array of disease states. Read more: Shi, Ge, Tianqing Liu, Zlatko Kopecki, Allison Cowin, Ivan Lee, Jing-Hong Pai, Sean E. Lowe, and Yu Lin Zhong. "A Multifunctional Wearable Device with a Graphene/Silver Nanowire Nanocomposite for Highly Sensitive Strain Sensing and Drug Delivery." Journal of Carbon Research C 5, no. 2 (2019): 17. https://www.mdpi.com/2311-5629/5/2/17

“Abstract: Advances in wearable, highly sensitive and multifunctional strain sensors open up new opportunities for the development of wearable human interface devices for various applications such as health monitoring, smart robotics and wearable therapy. Herein, we present a simple and cost-effective method to fabricate a multifunctional strain sensor consisting of a skin-mountable dry adhesive substrate, a robust sensing component and a transdermal drug delivery system. The sensor has high piezoresisitivity to monitor real-time signals from finger bending to ulnar pulse. A transdermal drug delivery system consisting of polylactic-co-glycolic acid nanoparticles and a chitosan matrix is integrated into the sensor and is able to release the nanoparticles into the stratum corneum at a depth of ~60 m. Our approach to the design of multifunctional strain sensors will lead to the development of cost-effective and well-integrated multifunctional wearable devices. Keywords: graphene; silver nanowire; multifunctional; wearable; strain sensor; drug delivery”

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