Poly(lactide)-diacrylate from PolySciTech used in patent describing development of advanced assay method

The ability to rapidly and accurately diagnose a disease state in a patient is critical as this guides the subsequent routes of treatment. A recent patent by Selux Diagnostics Inc. describes the use of PLA-diacrylate (AI036) from PolySciTech (www.polyscitech.com) to develop particles for assay applications. This research holds promise for improved assay methodologies across a wide array of applications including diagnostic applications. Read more: Stern, Eric, Aleksandar Vacic, Alec Nathanson Flyer, Benjamin Spears, and Susan Clardy. "Dissociable nanoparticles with inter alia transition-metal complex catalysts." U.S. Patent Application 15/745,361, filed March 28, 2019. https://patents.google.com/patent/US20190091673A1/en

“Abstract: Nanoparticles for use in assay methods for detecting analytes in samples, which comprise a signal inducing agent, e.g. a transition-metal catalyst or a chemiluminophore, a chemiluminophore precursor, a soluble absorber, or a soluble absorber precursor. After binding to an analyte, the nanoparticle is dissociated by a chemical or physical trigger, e.g. an organic solvent or ultrasound, to release the signal inducing agent, which releases a detectable signal via a physical or chemical reaction. The nanoparticles comprising a chemiluminophore, a chemiluminophore precursor, a soluble absorber, or a soluble absorber precursor can also effect chemical reactions that serve as signal amplifiers.”

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