PolySciTech (www.polyscitech.com)
provides a wide array of research polymers and precursors. In a recent
publication polyvivo AI10 (PLGA-NH2) was utilized for conjugation to CY5.5-NHS
stain to generate a PLGA-CY5.5 and this was mixed with PLGA (AP082) and
docetaxel to create drug loaded nanoparticles. These were embedded in
ceramic/hyaluronic acid structure to create a targeted nanoparticle. Read more:
Park, Ju-Hwan, Jae-Young Lee, Ubonvan Termsarasab, In-Soo Yoon, Seung-Hak Ko,
Jae-Seong Shim, Hyun-Jong Cho, and Dae-Duk Kim. "Development of poly
(lactic-co-glycolic) acid nanoparticles-embedded hyaluronic acid–ceramide-based
nanostructure for tumor-targeted drug delivery." International Journal of
Pharmaceutics (2014). http://www.sciencedirect.com/science/article/pii/S0378517314005377
Blog dedicated to answering technical questions in an open format relating to PolySciTech (A division of Akina, Inc.) products.
Wednesday, August 6, 2014
PolySciTech PolyVivo AI10 (PLGA-NH2) and AP082 (PLGA) used to develop hyaluronic acid–ceramide-PLGA nanoparticle for targeted cancer delivery of docetaxel
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